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ONCOGENE PROTEIN PP60(V-SRC)
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DeCS
Descriptor
English
:
Oncogene Protein pp60(v-src)
Descriptor
Spanish
:
Proteína Oncogénica pp60(v-src)
Descriptor
Portuguese
:
Proteína Oncogênica pp60(v-src)
Synonyms
English
:
Oncogene Protein pp60(src)
pp60(v-src)
src Oncogene Protein pp60
v-src Protein pp60
Tree Number:
D08.811.913.696.620.682.725.800.472
D12.776.624.664.520.750.760
D12.776.964.700.750.760
D12.776.964.775.750.760
Definition
English
:
A tyrosine-specific protein kinase encoded by the v-src oncogene of
ROUS SARCOMA VIRUS
. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal
tyrosine
phosphorylation
site at position 527, and the attachment of pp60(v-src) to the
plasma
membrane which is accomplished by myristylation of its N-terminal
glycine.
History Note
English
:
91; was ONCOGENE PROTEIN PP60(SRC) 1990; PP60(SRC) was see ONCOGENE PROTEIN PP60(SRC) 1990
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29308
Unique Identifier:
D015688
Occurrence in VHL
:
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